gap project portfolio » Cascade Prodrug
Project Title: Nanosystem for the delivery of Hypoxia-Activated-Prodrugs
Prinicipal Investigator: Adam Alani, Oregon State University
Company Principal: August Sick, Cascade Prodrug
Project Description: Cascade Prodrug, working with researchers from Oregon State University, is working to examine the key molecular mechanisms involved in the activation and function of lead anti-cancer compounds, specifically targeting tumor hypoxia using prodrugs. By selectively targeting tumor hypoxia for activation, the prodrugs are less toxic to nomral cells than the corresponding parent drugs thereby providing a safer, mor eeffetive cancer treatment. Data generated in this project will provide Cascade Prodrug with a clear path for drug development, attracting investors who need this critical information in order to provide the capital for Cascade Prodrug to build a product development team in Oregon.
Company Website: cascadeprodrug.com